Potato peels are rich in α-solanine and α-chaconine, which are glycoalkaloids with known pharmacological activity but that have high cytotoxicity. Their aglycones (β-solanine and β-chaconine) have the same pharmacological activity but with a much lower cytotoxicity. In this work, we applied ultrasound technology to extract α-solanine and α-chaconine from potato peel and at the same time convert these molecules into β-solanine and β-chaconine, in a single-stage process without resorting to organic solvents. The extraction was studied varying ultrasonic power density (20, 35, and 50 W/L) and processing time (5, 10, 20, and 40 min) using an ultrasonic bath operating at 25 kHz. The chemical analysis was done by UHPLC-qTOF-MS and the results were evaluated by HCA, PCA, and PLS-DA chemometric analysis. The analysis of the single-stage procedure pointed to the viability of concomitant extraction and chemical conversion of α-solanine and α-chaconine into β-solanine and β-chaconine when operating at an ultrasonic power density of 35 and 50 W/L and subjecting the potato peel power to 20 and 40 min of ultrasound.
CITATION STYLE
Alves-Filho, E. G., Sousa, V. M., Ribeiro, P. R. V., Rodrigues, S., de Brito, E. S., Tiwari, B. K., & Fernandes, F. A. N. (2018). Single-stage ultrasound-assisted process to extract and convert α-solanine and α-chaconine from potato peels into β-solanine and β-chaconine. Biomass Conversion and Biorefinery, 8(3), 689–697. https://doi.org/10.1007/s13399-018-0317-7
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