High-Resolution and Microscopic Imaging at High Field

Abstract

The goal of improved spatial resolution in magnetic resonance imaging for better visualization of finer and finer structural details in the body is driven by a long tradition of microscopy in conventional anatomy. Centuries of anatomical studies have underscored the success with which the study of function and dysfunction can be complemented by the study of normal and pathological structure. Since relevant structures in the body span spatial scales from meters to the subcellular level, imaging technology has been pushed toward increasing resolution. Although there are solid motivations for imaging biological samples and small animal models with MR, a principal attraction of MR technology is the potential that advances in methodology can ultimately be adapted for use in living humans.