Isolation of Synaptic Current

Abstract

Synaptic currents can be examined by a variety of different approaches such as isolating quantal currents or evoking currents using electrical or optical stimulation. It is important for a beginning electrophysiolo-gist to fully comprehend each approach so that the right method is used for the intended scientific question. Below we provide conceptual and technical information for miniature, spontaneous, quantal, and evoked postsynaptic currents with useful references that provide additional and in some cases more detailed information.