The glucuronoxylomannan component of the Cryptococcus neoformans capsular polysaccharide confers serotype specificity, and its detection in cerebrospinal fluid or serum by the latex agglutination test is used for diagnosis. Low-molecular-weight hydroxyethyl starches can be used as an alternative to albumin for vascular filling. This study reports the occurrence of a false-positive result with the Pastorex Cryptococcus test (Sanofi Diagnostics Pasteur, Marnes la Coquette, France) for a patient receiving hydroxyethyl starch characterized by a substitution ratio of 0.6 (Elohes, Biosedra, Sevres, France).
CITATION STYLE
Millon, L., Barale, T., Julliot, M. C., Martinez, J., & Mantion, G. (1995). Interference by hydroxyethyl starch used for vascular filling in latex agglutination test for cryptococcal antigen. Journal of Clinical Microbiology, 33(7), 1917–1919. https://doi.org/10.1128/jcm.33.7.1917-1919.1995
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