Nanobody-Based Delivery Systems for Diagnosis and Therapeutic Applications

Abstract

Nanobodies, also popularly known as nanomaterials, nanoparticles, etc., have found widespread applications in designing various smart delivery systems employed in disease diagnosis and therapeutic applications. Due to the rapid development in nanomaterial science and technology, such nanobodies are increasingly contributing to develop nanomedicines as well as nano delivery systems to treat ailments by achieving targeted and controlled delivery. These nanobodies have become the indispensable nanomaterials in disease diagnosis and treatment. This chapter deals with the introduction to such nanobodies, their contribution to overcome various challenges of drug delivery, exploitation of their optical properties for disease diagnosis, their use in nanomedicine formulations, and controlled delivery of therapeutics to targeted sites. The influence of shape, size, and architectures of such nanobodies on the efficacy of drug delivery is discussed. Their role in diagnosing diseases through bioimaging along with their response to external stimuli exploited for smart delivery is discussed. Finally, the challenges and prospects of these nanobodies are discussed.