Impacto do volume de gordura aspirado na resistência insulínica após lipoaspiração

Abstract

Objective: To investigate insulin resistance imposed by liposuction, correlating its intensity with the extent of the operation. Methods: The sample consisted of 20 female patients without comorbidities, aged between 21 and 43 years, body mass index between 19 and 27 kg/m2, undergoing liposuction alone or associated with breasts' prosthesis. We assessed insulin resistance at the beginning and end of the procedure by calculating the Homeostasis Model Assessment (HOMA-IR). The operative variables were length of liposuction, breast prosthesis time, body areas submitted to liposuction and total fat aspirated. Results: The liposuction time was 94-278 min (mean = 174 min), duration of breast prosthesis 20-140 min (mean = 65 min) and total fat aspirated 680-4280 g (mean = 1778 g). Statistical analysis was performed by considering a division line of 1500 g of aspirated fat and there was a significantly increased insulin resistance by HOMA index greater in the group > 1500 g (123% increase) than in the group d 1500 g (an increase of 53%) from the baseline data (p = 0.02). Other operative variables showed no significant correlation. Conclusion: Insulin resistance shows significant increase in liposuction, and it is correlated to the volume of aspirated fat.