Successful treatment of a solitary brain metastasis from small cell lung cancer with whole brain radiotherapy and stereotactic radiosurgery boost: A case report

Abstract

Small cell lung cancer (SCLC) is an aggressive disease with a high potential for brain metastases. Treatment for metastatic SCLC is systemic chemotherapy, but the median overall survival remains poor. Cranial irradiation for palliative purposes using whole brain radiotherapy is the standard-of-care for patients with symptomatic brain metastases. However, few reports showed a prolonged survival in SCLC patients with solitary brain metastasis treated with a definitive intent. We report a case of a 62-year-old man who presented with solitary brain metastasis secondary to SCLC who was successfully treated with definitive radiotherapy to the primary lesion and the solitary brain metastasis, and followed up for 2 years.