Background: Interventional medical devices based on thermally responsive shape memory polymer (SMP) are under development to treat stroke victims. The goals of these catheter-delivered devices include re-establishing blood flow in occluded arteries and preventing aneurysm rupture. Because these devices alter the hemodynamics and dissipate thermal energy during the therapeutic procedure, a first step in the device development process is to investigate fluid velocity and temperature changes following device deployment.Methods: A laser-heated SMP foam device was deployed in a simplified in vitro vascular model. Magnetic resonance imaging (MRI) techniques were used to assess the fluid dynamics and thermal changes associated with device deployment.Results: Spatial maps of the steady-state fluid velocity and temperature change inside and outside the laser-heated SMP foam device were acquired.Conclusions: Though non-physiological conditions were used in this initial study, the utility of MRI in the development of a thermally-activated SMP foam device has been demonstrated. © 2009 Small et al; licensee BioMed Central Ltd.
CITATION STYLE
Small IV, W., Gjersing, E., Herberg, J. L., Wilson, T. S., & Maitland, D. J. (2009). Magnetic resonance flow velocity and temperature mapping of a shape memory polymer foam device. BioMedical Engineering Online, 8. https://doi.org/10.1186/1475-925X-8-42
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