Phylogenetic background and carriage of pathogenicity island-like domains in relation to antibiotic resistance profiles among Escherichia coli urosepsis isolates

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Abstract

We studied 100 well-characterized E. coli blood isolates from patients with urosepsis for their susceptibility to nalidixic acid, ampicillin and trimethoprim-sulfamethoxazole, according to prevalence of virulence factors, phylogenetic groups and subgroups, PAI IIJ96-like domains (determined by physical linkage of cnf1, hly and hra) and PAI ICFT073-like domains (determined by physical linkage of papGII to the hly locus). Nalidixic acid resistance was associated with a lower prevalence of sfa/foc, K1 antigen, pathogenicity island IIJ96-like domains, subgroup B2/I and a shift towards group A. © 2006 Oxford University Press.

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Houdouin, V., Bonacorsi, S., Bidet, P., Bingen-Bidois, M., Barraud, D., & Bingen, E. (2006). Phylogenetic background and carriage of pathogenicity island-like domains in relation to antibiotic resistance profiles among Escherichia coli urosepsis isolates. Journal of Antimicrobial Chemotherapy, 58(4), 748–751. https://doi.org/10.1093/jac/dkl326

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