Chiral oxime ether 2 and Oxime ester 4 have been prepared by alkylation and esterification of the oxime 1. Racemic hydroxylamine 6 and chiral hydroxylamine 10 have been synthesised from N-hydroxysuccinimide and the corresponding alcohol in the presence of diethylazodicarboxylate, the two products were converted into the oxime ethers 7 and 11 respectively. The intramolecular radical cyclisation reactions of these oxime ethers and esters has been studied, successful reaction was observed to produce alkyl hydroxylamines 3, 8 and 12.
CITATION STYLE
Booth, S. E., Jenkins, P. R., & Swain, C. J. (1998). The preparation and intramolecular radical cyclisation reactions of chiral oxime ethers. Journal of the Brazilian Chemical Society, 9(4), 389–395. https://doi.org/10.1590/S0103-50531998000400012
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