Studies on the Metabolic Products of a Strain of Aspergillus fumigatus (DH 413). III. Biosynthesis of Toluquinones

Abstract

The relationship among the metabolites of Aspergillus fumigatus DH 413 was studied by using 14C-labelled compounds : 14C-Labelled 2-methyl-5-methoxy-6-hydroxy-2,3-epoxy-p-benzoquinone (III) was well incorporated into fumigatin and fumigatin quinol, but the reverse reaction was not observed, and it is suggested that the epoxydation step should be involved in the biosynthesis of toluquinones. © 1967, The Pharmaceutical Society of Japan. All rights reserved.