Improving the production of monensin by Streptomyces cinnamonensis

Abstract

The production of monensin by Streptomyces cinnamonensis was increased by genetic improvement of the strain and by modification of cultivation conditions. The selection of a suitable strain and optimization of the fermantation process (temperature, aeration, addition of esters of oleic acid) resulted in a 30 fold increase of the monensin production. © 1984 Institute of Microbiology, Academy of Sciences of the Czech Republic.