Schizophrenia and apolipoprotein e gene polymorphism in Serbian population

10Citations
Citations of this article
29Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Apolipoprotein E (APOE) gene variants are associated with alterations in brain function and increased risk of Alzheimer's disease (AD) and conflicting results have been reported in schizophrenia. Our results showed no significant differences in APOE allele or genotype frequencies between the Serbian schizophrenic patients and control individuals. However, we observed a possible association between particular subtypes of schizophrenia and APOE ε3/ε3 genotype (p = .01221) and ε4 allele showed a tendency toward positive association with responding to typical neuroleptics. APOE genotypes have no major influence on risk of schizophrenia, treatment and response to conventional antipsychotics, and age of onset in schizophrenia. Copyright © 2010 Informa Healthcare USA, Inc.

Cite

CITATION STYLE

APA

Kecmanović, M., Dobričić, V., Dimitrijević, R., Keckarević, D., Savić-Pavićević, D., Keckarević-Marković, M., … Romac, S. (2010). Schizophrenia and apolipoprotein e gene polymorphism in Serbian population. International Journal of Neuroscience, 120(7), 502–506. https://doi.org/10.3109/00207451003765956

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free