cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein

47Citations
Citations of this article
9Readers
Mendeley users who have this article in their library.

Abstract

The gene expression of granulocyte colony-stimulating factor (G-CSF) is induced by lipopolysaccharide (LPS). GPE1, a cis-controlling element of the G-CSF gene, functions as an LPS-responsive element. GPE1-binding protein (GPE1-BP), a leucine-zipper protein, did not independently activate G-CSF gene expression. Protein blot analysis with biotinylated GPE1-BP revealed that there were nuclear proteins that interact specifically with GPE1-BP. Three leucine-zipper proteins were isolated from mouse cDNA expression libraries by this method: NF-IL6, ATF4, and a novel ATF4-related ATFx. The interactions of these proteins with GPE1-BP may play key roles in G-CSF gene expression. © 1992.

Cite

CITATION STYLE

APA

Nishizawa, M., & Nagata, S. (1992). cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein. FEBS Letters, 299(1), 36–38. https://doi.org/10.1016/0014-5793(92)80094-W

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free