Chromatin immunoprecipitation assay (ChIP) has been frequently used to determine whether a transcriptional regulator can bind to a specific DNA element in the chromatin content of cells. Here, we describe a detailed protocol for this assay with hands-on tips based on our own experience in working on the transcriptional regulator and tumor suppressor p53. © 2013 Springer Science+Business Media New York.
CITATION STYLE
Liao, J. M., & Lu, H. (2013). ChIP for identification of p53 responsive DNA promoters. Methods in Molecular Biology, 962, 201–210. https://doi.org/10.1007/978-1-62703-236-0_17
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