Therapeutic strategies in fungal infections

Abstract

In the care of patients at risk for invasive aspergillosis (IA), candidiasis (IC), or other invasive fungal diseases (IFD), clinicians may consider different treatment strategies, i.e., prophylactic, pre-emptive, empiric, and targeted treatment. The choice of an appropriate strategy depends largely on the underlying risk of IFD and the availability of reliable diagnostic tools. Various clinical studies have been conducted to assess the clinical efficacy of different antifungals in the context of these strategies. This chapter aims to give an overview on the available basis of evidence. Finally, the reader will be provided with treatment recommendations for most standard risk populations and situations.