The present study was performed to explore the effect of aqueous extract of Aloe vera on behavioural parameters of pain. Pain assessment was performed by the tail-flick and formalin tests. A. vera (100 mg/kg, per oral (p.o.)) produced an insignificant decrease in the pain response in the tail-flick and formalin tests. Moreover, A. vera (200 and 400 mg/kg, p.o.) did not have significant effect on the tail-flick test. However, A. vera (200 and 400 mg/kg, p.o.) significantly decreased the second phase of the formalin-induced pain. Thus, these findings suggest that A. vera exerts its effect by a peripheral mechanism of action rather than central. © 2012 Springer Science+Business Media, LLC.
CITATION STYLE
Rathor, N., Mehta, A. K., Sharma, A. K., Mediratta, P. K., & Sharma, K. K. (2012). Acute effect of Aloe vera gel extract on experimental models of pain. Inflammation, 35(6), 1900–1903. https://doi.org/10.1007/s10753-012-9512-z
Mendeley helps you to discover research relevant for your work.