Abstract
We show that perdeuterated side chain of leucine amino acid and related compounds can serve as a useful structural reporter, suitable for studying proteins using two-dimensional infrared (2DIR) spectroscopy. Strong direct-coupling C-D/C=O and C-D/Am-II cross-peaks were measured by dual-frequency 2DIR in these compounds. The direct-coupling cross peaks were further enhanced up to 5 fold using the relaxation-assisted 2DIR method. The energy transport times (arrival times) and amplification factors were measured and used to assign the C-D absorption peaks and these assignments were compared with the results of anharmonic DFT calculations.
Author supplied keywords
Cite
CITATION STYLE
Naraharisetty, S. R. G., Kasyanenko, V. M., Zimmermann, J., Thielges, M., Romesberg, F. E., & Rubtsov, I. V. (2009). The 2DIR Spectroscopy on C-D Modes of Leucined10 Side Chain. In Springer Series in Chemical Physics (Vol. 92, pp. 592–594). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-540-95946-5_192
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
