AB0918 FACTORS ASSOCIATED WITH ACHIEVEMENT OF TARGET SERUM URIC ACID IN PATIENTS WITH NON-TOPHACEOUS GOUT ATTENDING PRIMARY CARE CLINICS.

Abstract

Results: Four hundred and twenty-six patients with gout participated in this study and 343 (80.5%) patients had non-tophaceous gout. Their mean age was 57.7 (±12.9) years. Majority were men (280 patients), Malay (260 patients) and had at least a secondary education (223 patients). There were high prevalence of cardiovascular co-morbidities; hypertension in 279 (81.3%), dyslipidaemia in 235 (68.5%), diabetes mellitus in 154 (44.9%) and obesity in 167 of 265 (63%). There were 280 patients diagnosed with gout for more than six months and 201 (71.8%) had recent SUA; 44 (21.9%) achieved target SUA and 157 (78.1%) did not achieve target SUA. The factors found to be significantly different between the two groups were age, ethnicity, education level, BMI and SUA level before ULT initiation. (Table 1) The mean allopurinol dose were similar between patients who achieved and did not achieve target SUA (191.3±80.8mg vs 197.1±72.5mg, p=0.56) despite significant difference in the mean SUA (301.5±70.3μmol/L vs 488.3±93.1μmol/L, p<0.01).