Density and optical properties of {ciprofloxacin hydrochloride + aqueous-ethanol} mixtures at 30°c

Abstract

The paper deals with the calculation of molar refraction (RM) and polarizability (α) of antibiotic drug ciprofloxacin hydrochloride (c = 0.001-0.029 mol·dm-3) solutions in ethanol-water mixtures of different compositions (30, 50, and 70% v/v) from measured density (ρ) and refractive index (n) at 30°C. The effect of drug concentration and composition of ethanol-water mixtures on density and optical properties of drug solutions has been described.