In this paper we propose a method for the nonrigid registration of contrast-enhanced dynamic sequences of magnetic resonance(MR) images. The algorithm has been developed with accuracy in mind, but also has a clinically viable execution time (i.e. a few minutes) as a goal. The algorithm is driven by multiresolution optical flow with the brightness consistency assumption relaxed, subject to a regularized best-fit within a family of transforms. The particular family of transforms we have employed uses a grid of control points and trilinear interpolation. We present validation results from a study simulating non-rigid deformation by a biomechanical model of the breast, with simulated uptake of a contrast agent. We further present results from applying the algorithm as part of a routine breast cancer screening protocol. © Springer-Verlag Berlin Heidelberg 2006.
CITATION STYLE
Froh, M. S., Barber, D. C., Brock, K. K., Plewes, D. B., & Martel, A. L. (2006). Piecewise-quadrilateral registration by optical flow - Applications in contrast-enhanced MR imaging of the breast. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 4191 LNCS-II, pp. 686–693). Springer Verlag. https://doi.org/10.1007/11866763_84
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