Sequence typing confirms that a predominant Listeria monocytogenes clone caused human listeriosis cases and outbreaks in Canada from 1988 to 2010

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Abstract

Human listeriosis outbreaks in Canada have been predominantly caused by serotype 1/2a isolates with highly similar pulsedfield gel electrophoresis (PFGE) patterns. Multilocus sequence typing (MLST) and multi-virulence-locus sequence typing (MVLST) each identified a diverse population of Listeria monocytogenes isolates, and within that, both methods had congruent subtypes that substantiated a predominant clone (clonal complex 8; virulence type 59; proposed epidemic clone 5 [ECV]) that has been causing human illness across Canada for more than 2 decades. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

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Knabel, S. J., Reimer, A., Verghese, B., Lok, M., Ziegler, J., Farber, J., … Gilmour, M. W. (2012). Sequence typing confirms that a predominant Listeria monocytogenes clone caused human listeriosis cases and outbreaks in Canada from 1988 to 2010. Journal of Clinical Microbiology, 50(5), 1748–1751. https://doi.org/10.1128/JCM.06185-11

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