Stem Cell Bioprinting: Functional 3D Neural Mini‐Tissues from Printed Gel‐Based Bioink and Human Neural Stem Cells (Adv. Healthcare Mater. 12/2016)

  • Gu Q
  • Tomaskovic‐Crook E
  • Lozano R
  • et al.
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Abstract

On page 1429 G. G. Wallace, J. M. Crook, and co-workers report the first example of fabricating neural tissue by 3D bioprinting human neural stem cells. A novel polysaccharide based bioink preserves stem cell viability and function within the printed construct, enabling self-renewal and differentiation to neurons and supporting neuroglia. Neurons are predominantly GABAergic, establish networks, are spontaneously active, and show a bicuculline induced increased calcium response.

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Gu, Q., Tomaskovic‐Crook, E., Lozano, R., Chen, Y., Kapsa, R. M., Zhou, Q., … Crook, J. M. (2016). Stem Cell Bioprinting: Functional 3D Neural Mini‐Tissues from Printed Gel‐Based Bioink and Human Neural Stem Cells (Adv. Healthcare Mater. 12/2016). Advanced Healthcare Materials, 5(12), 1428–1428. https://doi.org/10.1002/adhm.201670060

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