Critical Illness Neuromyopathy: Clinical, Electrophysiological, and Histological Diagnosis

Abstract

Acute neuromuscular complications are common during critical illness, particularly among the most severe intensive care unit (ICU) patients with prolonged stay and mechanical ventilation, and those developing sepsis and multiple organ dysfunctions [1]. Lung, kidney, brain, and the circulatory and coagulation systems are traditionally reported as the most common failing organs, but no organ is spared by the devastating inflammatory response, and peripheral nerves and muscles are no exception [2].