In the 1930-1950s surgical renal sympathectomy was used to treat severe hypertension [13]. Despite a successful lowering of blood pressure (BP) observed with surgical denervation, this technique was abandoned due to a relatively high morbidity and mortality, and as a result of the development of more effective oral antihypertensive medications.
CITATION STYLE
Fischell, T. A., Ghazarossian, V. E., & Vega, F. (2015). Perivascular renal denervation (pvrdTM): chemical renal denervation with micro-doses of ethanol using the peregrineTM renal denervation device. In Renal Denervation: A New Approach to Treatment of Resistant Hypertension (pp. 107–116). Springer-Verlag London Ltd. https://doi.org/10.1007/978-1-4471-5223-1_13
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