Preparation and evaluation of natural scaffold materials for kidney regenerative applications

Abstract

Tissue engineering involves the concerted action of biomaterials, cells, and growth factors. Kidney  regeneration relies on the same combination of ingredients. Here, we describe an example of gelatin-based biomaterial preparation and its evaluation in the context of kidney biocompatibility and integration. This biomaterial manufacturing technique is simple, cost-effective, highly reproducible and the in vivo evaluation procedure highly informative on the biocompatibility and regenerative potential of the tested construct. © 2013 Springer Science+Business Media New York.