Molecular evolution in time-dependent environments

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Abstract

The quasispecies theory is studied for dynamic replication landscapes. A meaningful asymptotic quasispecies is defined for periodic time dependencies. The quasispecies’ composition is constantly changing over the oscillation period. The error threshold moves towards the position of the time averaged landscape for high oscillation frequencies and follows the landscape closely for low oscillation frequencies.

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Wilke, C. O., Ronnewinkel, C., & Martinetz, T. (1999). Molecular evolution in time-dependent environments. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 1674, pp. 417–421). Springer Verlag. https://doi.org/10.1007/3-540-48304-7_57

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