Sedation for upper gastrointestinal endoscopy

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Abstract

Endoscopic procedures are performed using sedation. For prolonged and uncomfortable procedures supplementary sedation/analgesia may be required. The used anaesthetic agent should provide a rapid, smooth induction and quick recovery. Aim: To assess safety of sedation with Propofol as a sole agent for patients undergoing upper gas trointestinal endoseopy. Method: After evaluation of the patient's clinical condition we use Propofol titrated according to patient's response. Monitoring (Ps, RR, SpO2) was established, and oxygen was administered via nasal cannula. Propofol infusion was commenced at an initial rate of 1mg/kg, followed by increments of 0.2mg/kg to achieve an effect. Results: Cardiorespiratory parameters remained within safe acceptable limits throughout. No subjects required additional sedative. Oversedation with risk of respiratory depression we didn't observe. Conclusion: Propofol infusion at variable titratable rate can be used for prolonged endoscopic procedures. Continuous and careful observation by the anaesthesiologist is required. Pulse-oximetry is an useful monitor for detection of hypoxia during and after endoscopy.

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Cherkezov, J., Tzoneva, D., Vladimirov, B., & Karadimov, D. (2005). Sedation for upper gastrointestinal endoscopy. Anaesthesiology and Intensive Care, 32(5), 27–30. https://doi.org/10.1093/bja/52.8.811

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