The aim of this single-center prospective study was to assess the presence of Cheyne-Stokes respiration (CSR) and CSR-related variables in 68 consecutive patients with radiologically proven first-ever lacunar stroke undergoing a respiratory sleep study using a portable respiratory polygraph within the first 48 hours of stroke onset. CSR was diagnosed in 14 patients (20.6%). Patients with CSR as compared with those without CSR showed a significantly higher mean (standard deviation, SD) apnea-hypopnea index (AHI) (34.9 (21.7) versus 18.5 (14.4), P = 0.001 ) and central apnea index (13.1 (13.8) versus 1.8 (3.4), P = 0.0001 ) as well as higher scores of the Barthel index and the Canadian Neurological scale as a measure of stroke severity, and longer hospital stay. CSR was present in one of each five patients with lacunar stroke. The presence of CSR was associated with a trend towards a higher functional stroke severity and worse prognosis.
Bonnin-Vilaplana, M., Arboix, A., Parra, O., García-Eroles, L., Montserrat, J. M., & Massons, J. (2012). Cheyne-Stokes Respiration in Patients with First-Ever Lacunar Stroke. Sleep Disorders, 2012, 1–6. https://doi.org/10.1155/2012/257890