The World Health Organization (WHO) international standard (IS) for hepatitis B virus (HBV) DNA for use in nucleic acid amplification assays was characterized by determining the complete genome sequence, which was assigned genotype A. This information will aid the design, development, and evaluation of HBV DNA amplification assays.
Jenkins, A., Minhas, R., Morris, C., & Berry, N. (2017). Complete Genome Sequence of the WHO International Standard for Hepatitis B Virus DNA. Genome Announcements, 5(7). https://doi.org/10.1128/genomea.01576-16