Background: Since December 2019, the COVID-19 pandemic has changed the concept of medicine. This work aims to analyze the use of antibiotics in patients admitted to the hospital due to SARS-CoV-2 infection. Methods: This work analyzes the use and effectiveness of antibiotics in hospitalized patients with COVID-19 based on data from the SEMI-COVID-19 registry, an initiative to generate knowledge about this disease using data from electronic medical records. Our primary endpoint was all-cause in-hospital mortality according to antibiotic use. The secondary endpoint was the effect of macrolides on mortality. Results: Of 13,932 patients, antibiotics were used in 12,238. The overall death rate was 20.7% and higher among those taking antibiotics (87.8%). Higher mortality was observed with use of all antibiotics (OR 1.40, 95% CI 1.21–1.62; p
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Bendala Estrada, A. D., Calderón Parra, J., Fernández Carracedo, E., Muiño Míguez, A., Ramos Martínez, A., Muñez Rubio, E., … Núñez-Cortés, J. M. (2021). Inadequate use of antibiotics in the covid-19 era: effectiveness of antibiotic therapy. BMC Infectious Diseases, 21(1). https://doi.org/10.1186/s12879-021-06821-1
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