Various aspects of (recombinant) baculovirus production in insect-cell cultures are discussed. After a general introduction, the biology and the factors affecting the replication of the virus are covered. Then design considerations and production levels are discussed in view of large-scale production. Finally, the first attempts in modelling this complex process are treated.
CITATION STYLE
Tramper, J., Lier, F. L. J., Kool, M., Gooijer, C. D., & Vlak, J. M. (1992). Production of (Recombinant) Baculoviruses in Insect-Cell Bioreactors. In Recent Advances in Biotechnology (pp. 263–284). Springer Netherlands. https://doi.org/10.1007/978-94-011-2468-3_12
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