Flow Chemistry Set-up Enables Integration of Chemo- and Biocatalysis

Abstract

The move towards sustainable syntheses is a widespread effort which sees academia and industry developing new strategies and solutions. Flow chemistry, and in general the flow set-up, with the compartmentalization of different steps in dedicated reactors, offers new possibilities to integrate biocatalytic steps within a chemical cascade, often without the need to redesign the whole pathway. Here we report key examples in the field over the past few years.