Analgesic Effect of Xenon in Rat Model of Inflammatory Pain

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Abstract

The analgesic effects of inert gas xenon were examined on rats. The formalin model of inflammatory pain, tail-flick test, and hot-plate test revealed the antinociceptive effects of subanesthetizing doses of inhalation anesthetic xenon. Inhalation of 50/50 xenon/oxygen mixture moderated the nociceptive responses during acute and tonic phases of inflammatory pain.

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Kukushkin, M. L., Igon’kina, S. I., Potapov, S. V., & Potapov, A. V. (2017). Analgesic Effect of Xenon in Rat Model of Inflammatory Pain. Bulletin of Experimental Biology and Medicine, 162(4), 451–453. https://doi.org/10.1007/s10517-017-3637-x

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