Radical surgical treatment of neuroendocrine tumors of the appendix in children - A Polish multicenter study

Abstract

Introduction: The aim of the study was to examine management of pediatric appendiceal neuroendocrine tumors (ANETs) in Poland. Methods: Records of 27 patients with ANET diagnosed incidentally after appendectomy in the last decade. Results: Well-differentiated NET G1/G2 was diagnosed in 25 and well-differentiated neuroendocrine carcinoma G3 in 2 patients. Extended surgery was performed primarily in one instance and secondarily in 10 patients (right hemicolectomy in 9, ileocecal resection in 1) without adjuvant chemotherapy. Follow-up range was 1-121 months. Recurrence after secondary surgery was observed in 1 (3.7%) patient. Conclusions: Applying ENETS guidelines resulted in 100% overall survival of patients with NET.