Synthesis and antioxidant activity of water-soluble chitosan derivatives

Abstract

We prepared three different water-soluble chitosan derivatives by the acylation chitosan with corresponding acid anhydrides. The extent of acylation was determined by using the electric conductivity method. All of the chitosan derivatives were soluble enough to examine the respective antioxidant activity in aqueous media. The chitosan derivatives inhibited thiobarbituric acid reactive substrate (TBARS) formation in t -butyl hydroperoxide and benzoyl peroxide induced lipid peroxidations. However, they did not show any scavenging activity toward superoxide.