The Effects of Nano-honey Containing Hydroxyapatite on Socket Healing

Abstract

Background/Purpose: The aim of this study was to evaluate the effect of nano-honey containing calcium compounds on restoration of tooth socket. Material and Methods: Based on the placed substance on tooth socket, the samples were divided into two treated groups including nano-honey, nano-honey with calcium compounds and control group in which receiving no substance. Eight weeks of post-treatment, biopsy was performed and the type of epithelium, the type of connective tissue, the degree of inflammation, and the type of the bone in the alveolar crust were histologically compared between all groups. Results: Histological examination of 9 lamella of tooth sockets has revealed that there was no relationship in soft and hard tissue restoration between both treated group compared to the control group. The epithelial tissue in nano-honey contains calcium compounds group consisted of 33.3% normal epithelium and 66.7% squamous epithelium. The results have shown that both the nano-honey and control groups consisted of 33.3% fibrous and 66.7% granulation tissues. It has been observed that in nano-honey containing calcium compounds group, the inflammation rate was less than 10 in 66.7% of the cases and it was between10-30 in 33.3% of the cases. Examining the bone type in the alveolar crust has illustrated that it was seen that there was no normal bone and resorption in nano-honey containing calcium compounds group. In case of nano-honey and control groups, 33.3%normal bone and66.7% resorption were observed. Conclusion: Th