Research in the field of cell biology and biomedicine relies on technologies that fractionate cell populations and isolate rare cell types to high purity. A brief overview of methods and commercially available products currently used in cell separations is presented. Cell fractionation by size and density and highly selective affinity-based technologies such as affinity chromatography, fluorescence-activated cell sorting (FACS) and magnetic cell sorting are discussed in terms of throughput, yield, and purity.
CITATION STYLE
Scheper, T., Kumar, A., Galaev, I. Y., & Mattiasson, B. (2008). Cell Separation: Fundamentals, Analytical and Preparative Methods. Advances in biochemical engineering/biotechnology (Vol. 106, pp. 1–18). Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/17660999
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