The AIMS65 score compared with the Glasgow-Blatchford score in predicting outcomes in upper GI bleeding

Abstract

Introduction: We previously derived and validated the AIMS65 score, a mortality prognostic scale for upper GI bleeding (UGIB). Objective: To validate the AIMS65 score in a different patient population and compare it with the Glasgow-Blatchford risk score (GBRS). Design: Retrospective cohort study. Patients: Adults with a primary diagnosis of UGIB. Main Outcome Measurements: Primary outcome: inpatient mortality. Secondary outcomes: composite clinical endpoint of inpatient mortality, rebleeding, and endoscopic, radiologic or surgical intervention; blood transfusion; intensive care unit admission; rebleeding; length of stay; timing of endoscopy. The area under the receiver-operating characteristic curve (AUROC) was calculated for each score. Results: Of the 278 study patients, 6.5% died and 35% experienced the composite clinical endpoint. The AIMS65 score was superior in predicting inpatient mortality (AUROC, 0.93 vs 0.68; P