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Book Chapter

Analysis of Dose–Response Studies—Modeling Approaches

  • Pinheiro J
  • Bretz F
  • Branson M
Springer New York, (2006), 146-171
DOI: 10.1007/0-387-33706-7_10
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Abstract

Identifying the correct dose is one of the most important and difficult goals in drug development. Selecting too high a dose can result in an unacceptable toxicity pro- file, while selecting too lowa dose decreases the chance of it showing effectiveness in Phase III...

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Pinheiro, J. C., Bretz, F., & Branson, M. (2006). Analysis of Dose–Response Studies—Modeling Approaches. In Dose Finding in Drug Development (pp. 146–171). Springer New York. https://doi.org/10.1007/0-387-33706-7_10

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