Discrimination of cryptochirality in chiral isotactic polystyrene by asymmetric autocatalysis

Abstract

Chiral isotactic polystyrenes induce the enantioselective addition of diisopropylzinc to pyrimidine-5-carbaldehyde, affording the enantiomerically enriched pyrimidyl alkanol with the corresponding absolute configuration to that of cryptochiral polystyrenes in conjunction with asymmetric autocatalysis. © 2009 The Royal Society of Chemistry.