High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome

  • Barbosa D
  • Hochhegger B
  • Souza Jr. A
  • et al.
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Abstract

Abstract Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). Materials and Methods: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were ground-glass opacities (GGOs) and smooth inter- and intralobular septal thickening, found in all eight cases; however, the crazy-paving pattern was found in only three cases. Pleural effusion and peribronchovascular thickening were observed in five patients. The abnormalities were bilateral in all patients. Conclusion: The predominant HRCT findings in patients with HPS were GGOs and smooth inter- and intralobular septal thickening, which probably correlate with the histopathologic findings of pulmonary edema.Resumo Objetivo: Descrever os achados na tomografia computadorizada de alta resolução (TCAR) de pacientes com síndrome pulmonar do hantavírus. Materiais e Métodos: Revisamos, retrospectivamente, os achados tomográficos de oito pacientes portadores da síndrome pulmonar do hantavírus, todos do sexo masculino e com idade de 19 a 70 anos (média de 41,7 anos). O diagnóstico foi estabelecido por teste sorológico de ensaio de imunoabsorção enzimática em todos os pacientes. Dois radiologistas de tórax analisaram as imagens e decidiram em consenso. Resultados: Os achados predominantes na TCAR foram opacidades em vidro fosco e espessamento septal inter e intralobular, observados nos oito pacientes; porém, padrão de pavimentação em mosaico foi encontrado em apenas três deles. Derrame pleural e espessamento peribroncovascular foram observados em cinco pacientes. As anormalidades foram bilaterais em todos os pacientes. Conclusão: Opacidades em vidro fosco e espessamento septal inter e intralobular foram os achados predominantes na TCAR nos pacientes com síndrome pulmonar do hantavírus, o que, provavelmente, se correlaciona com achados histopatológicos de edema pulmonar.

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APA

Barbosa, D. de L., Hochhegger, B., Souza Jr., A. S., Zanetti, G., Escuissato, D. L., Meirelles, G. de S. P., … Marchiori, E. (2017). High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome. Radiologia Brasileira, 50(3), 148–153. https://doi.org/10.1590/0100-3984.2016.0093

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