Gastric per-oral endoscopic myotomy: Indications, technique, outcomes, and future directions

Abstract

After the clinical success of per-oral endoscopic myotomy (POEM) for treatment of achalasia cardia, the principle of submucosal tunneling and mucosal flap valve has been used in several other areas of the gastrointestinal tract. Gastric per-oral endoscopic pyloromyotomy (G-POEM, POEP, POP) is a relatively new procedure described for the treatment of refractory gastroparesis. This review discusses the indications, patient selection, pre-procedure workup, and procedure details of G-POEM. It also reviews the current literature on this procedure and provides insights and future directions for research on this topic.