Associations between arterial elasticity and markers of inflammation in healthy older women

Abstract

The purpose of this investigation was to examine the associations between circulating markers of inflammation and arterial elasticity in healthy older women. Participants were 50 women older than 60 years of age, body mass index 27±4, and physically untrained. Large artery elasticity, small artery elasticity, systemic vascular resistance, total vascular impedance, estimated cardiac output, and estimated cardiac index were determined using pulse contour analysis. Serum concentrations of tumor necrosis factor-α, C-reactive protein (CRP), and interleukin 6 were assessed. Results from Pearson's correlation revealed that tumor necrosis factor-α was inversely associated with large artery elasticity (-.426, p