In a structured treatment interruption (STI) trial, 3 of 23 patients in a CD4 cell count-guided treatment arm developed recurring thrombocytopenia associated with the interruption of antiretroviral therapy. All 3 patients had slightly low or normal platelet counts before initiating antiretroviral therapy. STI may play a role in inducing thrombocytopenia in patients with human immunodeficiency virus infection.
CITATION STYLE
Ananworanich, J., Phanuphak, N., Nuesch, R., Apateerapong, W., Rojnuckarin, P., Ubolyam, S., … Ruxrungtham, K. (2003). Recurring thrombocytopenia associated with structured treatment interruption in patients with human immunodeficiency virus infection. Clinical Infectious Diseases, 37(5), 723–725. https://doi.org/10.1086/376989
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