There are no established protocols for the optimum surgical margin required for salivary gland malignancies. Factors including histologic diagnosis and TNM stage have been shown to be important in prognosis and survival outcome and mandate special consideration of margin size. Salivary cancers are treated differently at different anatomic sites, and different histologic types show a propensity for major or minor glands. Low-grade malignancies are treated with soft tissue margins of 1 cm or less. The facial nerve is preserved unless infiltrated and encased. Adenoid cystic carcinoma and carcinoma ex pleomorphic adenoma require more complex planning to obtain negative margins.
Makary, R. F., Gopinath, A., Markiewicz, M. R., & Fernandes, R. (2017). Margin Analysis. Oral and Maxillofacial Surgery Clinics of North America, 29(3), 355–366. https://doi.org/10.1016/j.coms.2017.04.002