A PROSPECTIVE STUDY OF FACTORS RELATED TO PLATELET YIELD AMONG DONORS UNDERGOING PLATELETPHERSIS.

Abstract

Background: The transfusion of blood products is life saving especially at emergency conditions. The platelet transfusions helps in prevention of bleeding related complications and thus prevents morbidity and mortality in thrombocytopenic patients. Platelets are transfused by two methods i) by fractionation of whole blood and ii) by platelet apheresis. The quality of single donor platelets (SDP) in terms of yield influences platelet recovery in the recipient. Material and Methods: A sample of 360 donors were included in the study over a period of one and half year. Various donor-related factors were meticulously recorded prior to performing plateletpheresis. The aim was to identify donor factors that influence platelet yield. The plateletpheresis procedures were performed using Trima accel machine. A relationship between pre-donation donor variables and yield of platelets was studied using the Pearson correlation. Results: The mean platelet yield was 2.29 ± 0.43 x10 5