Herpesvirus cyprini: Thermal Effects on Pathogenicity and Oncogenicity

Abstract

Effects of thermal conditions on CHV infection were investigated both in vitro and in vivo. CHV multiplied in FHM cells at incubation temperatures from 10°C to 25°C, but not at 30°C, optimal temperature being 15-20°C. Experimental infection of CHV was done on carp fry under controlled water temperatures of 15, 20 and 25°C. The mortality of carp fry due to CHV infection was markedly high at 15°C and decreased with the increase in water temperature. A papilloma was formed after 11 weeks at all temperatures tested. A regression of the papilloma was observed by shifting water temperature from 7.5°C to 20, 25 and 30°C but no regression of papilloma was observed by the shift of water temperature from 7.5°C to 15°C. © 1993, The Japanese Society of Fish Pathology. All rights reserved.