The advancement of nirmatrelvir, the active ingredient in Paxlovid, from discovery to emergency use authorization was achieved in just 17 months, requiring an unprecedented rate of chemical process development.
CITATION STYLE
Allais, C., Connor, C. G., Do, N. M., Kulkarni, S., Lee, J. W., Lee, T., … Weekly, R. M. (2023). Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months. ACS Central Science, 9(5), 849–857. https://doi.org/10.1021/acscentsci.3c00145
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