OWEN: Aligning long collinear regions of genomes

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Abstract

Summary: OWEN is an interactive tool for aligning two long DNA sequences that represents similarity between them by a chain of collinear local similarities. OWEN employs several methods for constructing and editing local similarities and for resolving conflicts between them. Alignments of sequences of lengths over 106 can often be produced in minutes. OWEN requires memory below 20 L, where L is the sum of lengths of the compared sequences.

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APA

Ogurtsov, A. Y., Roytberg, M. A., Shabalina, S. A., & Kondrashov, A. S. (2002). OWEN: Aligning long collinear regions of genomes. Bioinformatics, 18(12), 1703–1704. https://doi.org/10.1093/bioinformatics/18.12.1703

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